Stereotactic radiosurgery is successful for RCC brain metastases

A recent study of 362 patients with brain metastases from renal cell carcinoma (RCC) were treated with stereotactic radiosurgery to remove the metastases. The researchers concluded that stereotactic radiosurgery is highly effective in patients with brain metastases from RCC, and concomitant use of tyrosine kinase inhibitors (TKIs), such as sunitinib and pazopanib, does not suggest […]

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ASCO 2019: Analysis of CARMENA trial results using IMDC risk groups

The results from CARMENA, a randomised phase III clinical trial to assess the importance of surgery to remove the kidney (nephrectomy) in people with metastatic kidney cancer, have been re-analysed and were presented at the 2019 American Society of Clinical Oncology (ACSO) annual meeting in Chicago this week. The original results showed that many people with […]

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Percutaneous cryoablation for stage T1b tumours

A recent study published in Cardiovascular and Interventional Radiology this month looked at the use of percutaneous cryoablation for stage T1b (4.1-7.0 cm) renal cell carcinoma (RCC). This non-invasive technique, which involves ‘freezing’ the tumour using fine needles inserted through the skin (percutaneous), has not yet been widely adopted. The current study investigated the safety, […]

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Cryoablation versus partial nephrectomy for early stage renal masses

A recent study, published in the Journal of Cancer, conducted a systematic review and meta-analysis of the outcomes data for the use of cryoablation versus partial nephrectomy for early stage (T1) renal tumours. The review showed that cryoablation is linked with poorer oncologic outcomes than partial nephrectomy, but patients who underwent cryoablation had lower rates […]

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Microwave ablation for early stage renal masses

Researchers from the Mayo Clinic in Rochester, USA, have published a retrospective review of the use of microwave ablation in the American Journal of Roentgenology (AJR). The review describes percutaneous (through the skin) microwave ablation as a promising treatment for patients with early stage (T1) renal tumours. However, more research into the selection of patients due to […]

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ASCO GU 2019: Questions and lessons moving forward from CARMENA: A medical oncologist’s perspective

The following paper was presented at the American Society for Clinical Oncology (ASCO) genitourinary (GU) conference in San Francisco in February 2019. Cytoreductive nephrectomy (CN) is defined as the surgical removal of the primary renal cell carcinoma (RCC) tumour before starting systemic therapy. The following paper from medical oncologist Dr Lauren Harshman, Dana-Farber Cancer Institute, Boston, USA, suggests that this is an […]

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ASCO GU 2019: Patient perspectives on cytoreductive nephrectomy after CARMENA

The following survey assessed patient views related to cytoreductive nephrectomy following publication of the results of the CARMENA trial, and were reported at the American Society of Clinical Oncology (ASCO) genitourinary (GU) conference held in San Francisco in February 2019. The survey found that overall survival should not be overestimated as the most important aim […]

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ASCO GU 2019: Questions and lessons moving forward from CARMENA: A surgeon’s perspective

The following paper was presented at the American Society for Clinical Oncology (ASCO) genitourinary (GU) conference in San Francisco in February 2019. Cytoreductive nephrectomy (CN) is defined as the surgical removal of the primary renal cell carcinoma (RCC) tumour before starting systemic therapy. The following paper from surgeon Dr Paul Russo, Memorial Sloan Kettering Cancer […]

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Biopsy of small renal massess

The question as to whether to biopsy small renal masses or not is debated by two kidney cancer experts; Professor Jaime Landman from University of California Irvine Medical Centre in the US, and Professor Michael Staehler from the Ludwig- Maximilian University in Munich, Germany.  The experts discuss whether patients with small renal masses should be […]

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Stereotactic radiosurgery for multiple kidney cancer brain metastases

A recent study published in Clinical Genitourinary Cancer has shown that stereotactic radiosurgery (SRS) is effective for controlling renal cell carcinoma (RCC) brain metastases, although the effectiveness of SRS is not so good with larger metastatic tumours. In the study, more than half of the patients treated with SRS survived beyond a year, and there were […]

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