Kidney cancer surgery in older patients

The RESURGE project retrospectively analysed data from three published studies including 1871 patients with renal cell carcinoma (RCC) from 24 hospitals. This study looked at outcomes of surgery (radical or partial nephrectomy) in older patients aged over 75 years. The study concluded that surgery for kidney cancer is feasible and safe in well-selected older patients. […]

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Treatment with stereotactic body radiotherapy plus TKIs or immunotherapy is safe and may improve survival of metastatic kidney cancer patients

Two small studies looked at the addition of a type of radiotherapy treatment, called stereotactic body radiotherapy (SBRT), to treatment with a tyrosine kinase inhibitor (TKI), such as sunitinib or pazopanib, or a checkpoint inhibitor, such as nivolumab for patients with metastatic renal cell carcinoma (RCC). In the first study, 56 patients with metastatic RCC […]

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Incidence and pattern of recurrence of kidney cancer after robotic partial nephrectomy

A recent study has shown the incidence and pattern of recurrence of renal cell carcinoma (RCC) in patients who underwent robotic partial nephrectomy for a small renal mass between September 2009 and March 2018. A total of 335 patients with a small renal mass underwent robotic partial nephrectomy, 269 patients of which were found to […]

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Microwave ablation is feasible for early stage kidney cancer

A recent study published in the journal Urology has shown that microwave ablation is a feasible alternative to nephrectomy in selected patients with early stage renal cell carcinoma (RCC) tumours that are between 4 to 7 cm in diameter. In the study, 325 patients with early stage T1b RCC had either percutaneous (through the skin) […]

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Comparing outcomes for microwave ablation versus surgery in early stage kidney cancer

A recent study, published in the journal Urology this month, compares outcomes for patients with early stage T1b renal cell carcinoma (RCC) following treatment with microwave ablation, partial nephrectomy or radical nephrectomy. The study included a total of 325 patients; 40 underwent microwave ablation, 74 had partial nephrectomy and 211 had radical nephrectomy. Length of […]

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Comparing long-term outcomes for partial and radical nephrectomy

Using the National Cancer Database, 3009 patients with low stage renal cell carcinoma (RCC) were identified as having undergone radical (2454 patients) or partial (555 patients) nephrectomy and were younger than 50 years. Median follow-up was 108.6 months during which 297 patients (12.1%) in the radical nephrectomy arm and 58 patients (10.5%) in the partial nephrectomy […]

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Outcomes following partial nephrectomy and percutaneous ablation for small renal masses

A study published in European Urology presents retrospective data from the Mayo Clinic in America regarding their experience with partial nephrectomy, percutaneous radiofrequency ablation (RFA) and percutaneous cryoablation for small renal masses (less than 4 cm, stage cT1). Long-term follow-up data from 1798 patients with primary cT1N0M0 renal tumours were treated with partial nephrectomy, RFA […]

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Role of stereotactic ablative radiotherapy for primary renal cell carcinoma

This paper reviews the use of stereotactic ablative radiotherapy (SABR) (also called stereotactic body radiotherapy, SBRT) for treating primary renal cell carcinoma (RCC) that cannot be removed with surgery. SABR is a treatment that automatically targets high doses of radiotherapy to the tumour with high precision. SABR is very accurate, and thereby maximises the cell-killing […]

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Role of stereotactic ablative radiotherapy (SABR) for kidney cancer

This systematic review and meta-analysis of the literature for the use of stereotactic ablative radiotherapy (SABR) for renal cell carcinoma (RCC), looks at data from 372 patients (383 tumours), most of whom were inoperable. The study concluded that renal SABR is effective locally and is well tolerated for primary RCC, despite treatment of larger tumours […]

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The role of cytoreductive nephrectomy in metastatic kidney cancer

Around 12,500 new cases of renal cell carcinoma (RCC) are diagnosed annually in the UK, and about a third of these cases initially present with cancer that has spread to other parts of the body (non-localised or metastatic). Non-localised RCC has significantly worse 5-year survival outcomes compared with localised disease. The treatment options for patients […]

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