ASCO 2020: Factors influencing outcomes in kidney cancer treated with immunotherapy

A study presented during the 2020 American Society of Clinical Oncology (ASCO) Virtual Scientific Program has identified several features of kidney cancer tumours that influence their response to immune checkpoint inhibitors, such as nivolumab and pembrolizumab. The research was conducted at the Dana-Farber Cancer Institute in America and is published in the journal, Nature Medicine. […]

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Research suggests that B cells also play a role in the response to immunotherapy

A recent paper published in the journal Nature earlier this year shed some light on why some patients with soft-tissue sarcoma survived longer than others. The researchers expected that it came down to which patients had the most T cells, an immune cell known to contribute to the success of immunotherapy. However, after studying the […]

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Scientists discover a part of the immune system that may be used to treat all cancers

Scientists from the University of Cardiff have discovered part of our immune system that could potentially be harnessed to treat all types of cancer. This potential treatment has not yet been tested in humans, but has been shown to kill prostate, breast, lung and other cancers in the laboratory. Researchers suggest that the treatment has […]

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Fat near kidney tumours plays a critical role in treatment response

It is already known that obesity increases the risk of developing kidney cancer. However, obese people seem to do better after treatment compared with people of normal weight. Researchers at Memorial Sloan Kettering Cancer Center in New York have discovered that the fat surrounding kidney tumours may play a key role in the effectiveness of […]

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Computer-designed interleukin 2 (IL 2) without the side effects?

Interleukin-2 (IL2) is a naturally-occurring biological therapy called a cytokine. Cytokines boost the immune system and have been used to treat metastatic renal cell carcinoma (RCC) since the 1990s; however, its use has been limited by toxic side effects. Recently, scientists have been working to improve IL2. Researchers at the University of Washington, US, have […]

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