Local and regional recurrences of localised kidney cancer after nephrectomy

In this study 15 years of data from a single hospital were assessed to look at the outcomes of people who had had surgery for localised renal cell carcinoma (RCC). Of the 1895 people who were assessed, 30 (1.6%) had a single local recurrence of their cancer without distant spread (metastases). In total, 26 of […]

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Potential biomarker to predict risk of recurrence after nephrectomy for locally advanced kidney cancer

Currently, the search for a reliable biomarker to identify those patients who are at risk of the cancer coming back after nephrectomy for renal cell carcinoma (RCC) has not been successful. A recent study looked at a protein called kidney injury molecule-1 (KIM-1) in patients with RCC and whether this protein could be used to […]

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Predictive factors for recurrence after complete metastasectomy in metastatic kidney cancer patients

In this retrospective study, published in Science Direct this month, researchers were looking to identify the factors that would help to predict whether the cancer would come back after surgical removal of renal cell carcinoma (RCC) metastases (metastasectomy). Complete metastasectomy is expected to improve the survival of patients with metastatic RCC. However, for many patients […]

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Microwave ablation is feasible for early stage kidney cancer

A recent study published in the journal Urology has shown that microwave ablation is a feasible alternative to nephrectomy in selected patients with early stage renal cell carcinoma (RCC) tumours that are between 4 to 7 cm in diameter. In the study, 325 patients with early stage T1b RCC had either percutaneous (through the skin) […]

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Comparing outcomes for microwave ablation versus surgery in early stage kidney cancer

A recent study, published in the journal Urology this month, compares outcomes for patients with early stage T1b renal cell carcinoma (RCC) following treatment with microwave ablation, partial nephrectomy or radical nephrectomy. The study included a total of 325 patients; 40 underwent microwave ablation, 74 had partial nephrectomy and 211 had radical nephrectomy. Length of […]

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Metastasectomy followed by targeted therapy does not improve survival

The following video interview with Dr Elizabeth Plimack from the Fox Chase Cancer Center in Philadelphia, USA discusses the results from a study that assessed the outcome of metastasectomy in patients with metastatic renal cell carcinoma (RCC). The study looked at patients with slow growing disease, and maybe one metastasis that was removed with surgery. […]

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Sorafenib versus observation following surgery for metastatic kidney cancer

A potential treatment for a selected group of patients with metastatic renal cell carcinoma (RCC) is nephrectomy followed by surgery to remove metastases (radical metastasectomy). After surgery, patients are usually followed by observation or treated with anti-cancer drugs. The RESORT clinical trial assessed the potential benefit of treatment with sorafenib after radical metastasectomy compared with […]

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