Partial nephrectomy for patients with rare Xp11.2 translocation kidney cancer

XP11.2 translation renal cell carcinoma (RCC) is a very rare and aggressive subtype of RCC. Currently, partial nephrectomy can be used for treating kidney cancer at an early stage (T1a and T1b stage). Although partial nephrectomy can remove primary kidney tumours completely, there is always a risk of the tumour coming back because not all […]

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Evidence in favour of active surveillance for small renal masses

Two studies presented at the American Urological Association 2020 Virtual Experience this month provide evidence that active surveillance for small renal masses among older patients is as effective as surgery in terms of survival for patients with suspected renal cell carcinoma (RCC). In a study from Oxford University Hospitals 208 patients with 212 T1a small […]

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Female kidney cancer patients undergoing surgery for non-metastatic disease may have more favourable prognosis

A retrospective analysis of over 2000 patients from the International Marker Consortium for Renal Cancer (INMARC) database showed that female patients with non-metastatic clear cell renal cell carcinoma (ccRCC) had lower grade, lower stage, and longer relapse-free survival after partial or radical nephrectomy for their cancer. In conclusion, this study suggests that female patients with […]

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A potential biomarker for survival for non-metastatic kidney cancer

A recent study published in the journal International Urology and Nephrology this month evaluates mean platelet volume-to-lymphocyte ratio (MPVLR) as a biomarker for survival in patients undergoing nephrectomy for non-metastatic clear cell renal cell carcinoma (ccRCC). In the study, 344 patients with proven ccRCC that has not spread (non-metastatic) were treated with radical or partial […]

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Association of anxiety and depression with outcomes for kidney cancer patients undergoing nephrectomy

A recent retrospective study of 1990 adults who had a radical or partial nephrectomy for clear cell renal cell carcinoma (RCC) looked at the association between anxiety or depression and survival. Patients with anxiety or depression prior to or at the time of surgery (197 patents, 10%) had significantly more complications 30 days after surgery. […]

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Kidney cancer surgery in older patients

The RESURGE project retrospectively analysed data from three published studies including 1871 patients with renal cell carcinoma (RCC) from 24 hospitals. This study looked at outcomes of surgery (radical or partial nephrectomy) in older patients aged over 75 years. The study concluded that surgery for kidney cancer is feasible and safe in well-selected older patients. […]

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Microwave ablation is feasible for early stage kidney cancer

A recent study published in the journal Urology has shown that microwave ablation is a feasible alternative to nephrectomy in selected patients with early stage renal cell carcinoma (RCC) tumours that are between 4 to 7 cm in diameter. In the study, 325 patients with early stage T1b RCC had either percutaneous (through the skin) […]

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Comparing outcomes for microwave ablation versus surgery in early stage kidney cancer

A recent study, published in the journal Urology this month, compares outcomes for patients with early stage T1b renal cell carcinoma (RCC) following treatment with microwave ablation, partial nephrectomy or radical nephrectomy. The study included a total of 325 patients; 40 underwent microwave ablation, 74 had partial nephrectomy and 211 had radical nephrectomy. Length of […]

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Comparing long-term outcomes for partial and radical nephrectomy

Using the National Cancer Database, 3009 patients with low stage renal cell carcinoma (RCC) were identified as having undergone radical (2454 patients) or partial (555 patients) nephrectomy and were younger than 50 years. Median follow-up was 108.6 months during which 297 patients (12.1%) in the radical nephrectomy arm and 58 patients (10.5%) in the partial nephrectomy […]

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Radical versus partial nephrectomy and subsequent hypertension risk

In a recent study, the data from a database were analysed retrospectively to evaluate the onset or worsening of high blood pressure (hypertension) following partial versus radical nephrectomy. 3106 patients who did not have hypertension before nephrectomy had an increased risk of developing hypertension after radical nephrectomy. In 6250 patients who already had hypertension, radical […]

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