Association of anxiety and depression with outcomes for kidney cancer patients undergoing nephrectomy

A recent retrospective study of 1990 adults who had a radical or partial nephrectomy for clear cell renal cell carcinoma (RCC) looked at the association between anxiety or depression and survival. Patients with anxiety or depression prior to or at the time of surgery (197 patents, 10%) had significantly more complications 30 days after surgery. […]

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Partial nephrectomy for kidney cancer

At the recent Society of Urologic Oncology (SUO) conference in Washington, USA, Dr Steven Campbell reviewed the controversial topic of nephron-sparing surgery (partial nephrectomy) for stage cT1b-T2 kidney masses, i.e. tumours that are confined to the kidney but which are greater than 4 cm in diameter. Partial nephrectomy is recommended for small renal masses (stage […]

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Kidney cancer surgery in older patients

The RESURGE project retrospectively analysed data from three published studies including 1871 patients with renal cell carcinoma (RCC) from 24 hospitals. This study looked at outcomes of surgery (radical or partial nephrectomy) in older patients aged over 75 years. The study concluded that surgery for kidney cancer is feasible and safe in well-selected older patients. […]

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Microwave ablation is feasible for early stage kidney cancer

A recent study published in the journal Urology has shown that microwave ablation is a feasible alternative to nephrectomy in selected patients with early stage renal cell carcinoma (RCC) tumours that are between 4 to 7 cm in diameter. In the study, 325 patients with early stage T1b RCC had either percutaneous (through the skin) […]

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Comparing outcomes for microwave ablation versus surgery in early stage kidney cancer

A recent study, published in the journal Urology this month, compares outcomes for patients with early stage T1b renal cell carcinoma (RCC) following treatment with microwave ablation, partial nephrectomy or radical nephrectomy. The study included a total of 325 patients; 40 underwent microwave ablation, 74 had partial nephrectomy and 211 had radical nephrectomy. Length of […]

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Comparing long-term outcomes for partial and radical nephrectomy

Using the National Cancer Database, 3009 patients with low stage renal cell carcinoma (RCC) were identified as having undergone radical (2454 patients) or partial (555 patients) nephrectomy and were younger than 50 years. Median follow-up was 108.6 months during which 297 patients (12.1%) in the radical nephrectomy arm and 58 patients (10.5%) in the partial nephrectomy […]

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Outcomes following partial nephrectomy and percutaneous ablation for small renal masses

A study published in European Urology presents retrospective data from the Mayo Clinic in America regarding their experience with partial nephrectomy, percutaneous radiofrequency ablation (RFA) and percutaneous cryoablation for small renal masses (less than 4 cm, stage cT1). Long-term follow-up data from 1798 patients with primary cT1N0M0 renal tumours were treated with partial nephrectomy, RFA […]

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Radical versus partial nephrectomy and subsequent hypertension risk

In a recent study, the data from a database were analysed retrospectively to evaluate the onset or worsening of high blood pressure (hypertension) following partial versus radical nephrectomy. 3106 patients who did not have hypertension before nephrectomy had an increased risk of developing hypertension after radical nephrectomy. In 6250 patients who already had hypertension, radical […]

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Neoadjuvant axitinib to allow partial nephrectomy of cT2a renal tumours

A phase 2 study published in the British Journal of Urology last year evaluated the effectiveness of neoadjuvant axitinib given before surgery to reduce the size of renal tumours (stage cT2a) to enable partial nephrectomy in 18 patients. The tumours decreased in size in 16 of the 18 patients, and these 16 patients had a […]

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Percutaneous ablation for localised kidney tumours

A recent study reported in European Urology by investigators at the Mayo Clinic in Rochester, Minnesota, USA compared partial nephrectomy with percutaneous ablation (radiofrequency ablation or cryoablation) in the treatment of 1422 patients with localised renal tumours, stage cT1. Patients were followed for at least 6 years. There were no significant differences in local recurrence, […]

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