Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

In a study published in Cancer Cell last week, researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumours that can help predict if patients with kidney cancerĀ will respond to immunotherapy. The scientists looked at 115 tumour samples from 15 people with metastatic clear […]

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Immunotherapy and COVID-19 in cancer patients

A recent review published in the Journal for ImmunoTherapy of Cancer looks at the implications of people with renal cell carcinoma (RCC) taking immune checkpoint inhibitors and contracting the SARS-CoV-2 virus. Cancer patients are considered at high risk during the coronavirus pandemic. However, this review states that, although additional studies are needed, the most up-to-date […]

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ASCO 2020: Factors influencing outcomes in kidney cancer treated with immunotherapy

A study presented during the 2020 American Society of Clinical Oncology (ASCO) Virtual Scientific Program has identified several features of kidney cancer tumours that influence their response to immune checkpoint inhibitors, such as nivolumab and pembrolizumab. The research was conducted at the Dana-Farber Cancer Institute in America and is published in the journal, Nature Medicine. […]

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Research suggests that B cells also play a role in the response to immunotherapy

A recent paper published in the journal Nature earlier this year shed some light on why some patients with soft-tissue sarcoma survived longer than others. The researchers expected that it came down to which patients had the most T cells, an immune cell known to contribute to the success of immunotherapy. However, after studying the […]

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Fat near kidney tumours plays a critical role in treatment response

It is already known that obesity increases the risk of developing kidney cancer. However, obese people seem to do better after treatment compared with people of normal weight. Researchers at Memorial Sloan Kettering Cancer Center in New York have discovered that the fat surrounding kidney tumours may play a key role in the effectiveness of […]

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