Genetic profiling of renal medullary carcinoma paves the way for a potential treatment

Renal medullary carcinoma (RMC) is an aggressive cancer that mainly affects young people of African descent. It is resistant to all targeted agents used to treat other renal cell carcinomas (RCCs) and has limited therapeutic options. This study, published in the journal Cancer Cell analyses the genes of people with renal medullary carcinoma and finds […]

read more

New study shows causes of previously unexplained cancers

An “unprecedented” study has revealed the most comprehensive map of cancer genomes to date. This has enables scientists to discover the genetic causes of some previously unexplained cancers. The research was carried out by an international team involving more than 1,300 scientists and clinicians from 37 countries, who analysed more than 2,600 genomes of 38 […]

read more

New subtypes of kidney cancer identified

Using advanced proteogenomic technologies to look at genetic makeup and proteins, researchers from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) in America have identified four subtypes of clear cell renal cell carcinoma (RCC). The researchers found that almost all of the clear cell RCC tumour samples in the study lacked chromosome 3p. […]

read more

NHS to fast-track cancer drugs that target genetic mutations

The NHS is preparing to fast-track the introduction of ‘game changing’ new cancer drugs that target tumours according to their genetic make-up. These revolutionary new treatments, called ‘tumour agnostic’ drugs, can be used against a wide range of cancers and could offer hope to patients with rare cancers that may previously have been untreatable. Tumour […]

read more

Clinical characteristics and genomic alterations associated with outcome in chromophobe RCC

A recent study by researchers in New York, USA, and published in Clinical Genitourinary Cancer identified gene alterations and clinical characteristics that could help predict outcome in patients with a rare form of renal cell carcinoma (RCC) called chromophobe RCC. These gene alterations and clinical characteristics could also help identify potential targeted therapy options in […]

read more

Advanced Kidney Cancer Centre of Excellence

The Advanced Kidney Cancer Center of Excellence from UroToday and GU OncToday delivers disease, treatment and guidelines information in this rapidly changing area. This series of articles explores ongoing clinical trials, including trials looking at biomarkers and genomic data, in addition to live conference coverage that will provide real-time perspectives from Dr Sumanta Kumar Pal and […]

read more

Scientists discover a genetic cause of childhood kidney cancer

Scientists at The Institute of Cancer Research (ICR), London, and the Hubrecht Institute-KNAW in the Netherlands have identified a new genetic cause of a childhood kidney cancer called Wilms tumour, revealing insights into how loss of control of chromosome number can lead to cancer. Their study will help parents understand why their children have developed cancer […]

read more

The 100,000 Genomes Project

An ambitious project to sequence 100,000 genomes is making great progress: All 13 NHS Genomic Medicine Centres are recruiting rare disease and cancer patients to the project, and initiatives in Scotland, Northern Ireland and Wales are joining this world leading programme. There are nearly 20,000 genomes in the project’s datacentre, and the research groups are collaborating with the National […]

read more

Largest genomic study of kidney cancer

  Researchers in America have recently completed a study that analysed close to 900 kidney cancers at the molecular level. The team discovered that what have historically been considered three major types of kidney cancer according to their characteristics under the microscope (clear cell, papillary and chromophobe), could be further classified into nine major subtypes through molecular […]

read more
Showing all 9 results
  TOP