Scientists at the Wellcome Sanger Institute in Cambridge have discovered the earliest genetic root for the childhood kidney cancer, Wilms’ tumour. By comparing genome sequences from normal kidney tissue and tumours, the team identified patches of normal-looking kidney tissue that in fact carried DNA changes that cause Wilms’ tumour. The study identified a novel root […]
The MD Anderson Cancer Center (MDACC) 13th Update on the Management of Genitourinary Malignancies Conference took place in Houston, Texas at the end of last week (9-10 November). Kidney cancer highlights from the meeting have been published by UroToday. You can read more online on UroToday below: MDACC 2018: Promising Emerging Systemic Therapies for mRCC MDACC […]
A recent article in JAMA Oncology, published this month, discusses the use of gene sequencing to identify drug targets in tumours. Gene sequencing has led to incidental findings of germline mutations in patients; changes in the genes of the germ cells that form eggs and sperm and are eventually passed on to the next generation. […]
Scientists working on a Cancer Research UK funded study have discovered that the development of kidney cancer follows distinct paths, which can begin in childhood. These evolutionary paths enable scientists to detect whether a tumour will be aggressive and spread. “We could use these rules to help choose the best treatments, and potentially to diagnose some […]
Scientists at The Institute of Cancer Research (ICR), London, and the Hubrecht Institute-KNAW in the Netherlands have identified a new genetic cause of a childhood kidney cancer called Wilms tumour, revealing insights into how loss of control of chromosome number can lead to cancer. Their study will help parents understand why their children have developed cancer […]
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