Immune cell helps prevent kidney cancer recurrence

Recurrence occurs when cancer comes back after surgery, or after a period of time being cancer-free. For people with clear cell renal cell carcinoma (RCC), the most common type of kidney cancer, the recurrent cancer can spread and develop into metastatic disease, despite treatment. A new study from researchers at Columbia University in the USA […]

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Root of childhood kidney cancer

Scientists at the Wellcome Sanger Institute in Cambridge have discovered the earliest genetic root for the childhood kidney cancer, Wilms’ tumour. By comparing genome sequences from normal kidney tissue and tumours, the team identified patches of normal-looking kidney tissue that in fact carried DNA changes that cause Wilms’ tumour. The study identified a novel root […]

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MD Anderson Cancer Center 13th Update on the Management of Genitourinary Malignancies Conference

The MD Anderson Cancer Center (MDACC) 13th Update on the Management of Genitourinary Malignancies Conference took place in Houston, Texas at the end of last week (9-10 November). Kidney cancer highlights from the meeting have been published by UroToday. You can read more online on UroToday below: MDACC 2018: Promising Emerging Systemic Therapies for mRCC MDACC […]

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The implications of germline mutations in kidney cancer

A recent article in JAMA Oncology, published this month, discusses the use of gene sequencing to identify drug targets in tumours. Gene sequencing has led to incidental findings of germline mutations in patients; changes in the genes of the germ cells that form eggs and sperm and are eventually passed on to the next generation. […]

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Kidney cancer may begin to develop in childhood

Scientists working on a Cancer Research UK funded study have discovered that the development of kidney cancer follows distinct paths, which can begin in childhood. These evolutionary paths enable scientists to detect whether a tumour will be aggressive and spread. “We could use these rules to help choose the best treatments, and potentially to diagnose some […]

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Scientists discover a genetic cause of childhood kidney cancer

Scientists at The Institute of Cancer Research (ICR), London, and the Hubrecht Institute-KNAW in the Netherlands have identified a new genetic cause of a childhood kidney cancer called Wilms tumour, revealing insights into how loss of control of chromosome number can lead to cancer. Their study will help parents understand why their children have developed cancer […]

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