Differences in survival with tremelimumab due to different types of kidney cancer

Most people have a type of kidney cancer called clear cell renal cell carcinoma (RCC). A recent study has shown that people with clear cell RCC have a better response to tremelimumab (an anti-CTLA-4 antibody) compared with patients with non-clear cell RCC following a procedure called cryoablation (freezing the tumour using probes through the skin). […]

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Cryoablation versus partial nephrectomy for T1 kidney tumours

In this study published in Science Direct, the researchers compared kidney function and cancer outcomes in patients having percutaneous (through the skin) cryoablation or partial nephrectomy using a laparoscope for small renal tumours (stage T1). Ninety (90) patients had cryoablation and 90 had partial nephrectomy. Patients were matched for demographics, baseline renal function, and the […]

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Cryoablation comparable to surgery for treating early-stage kidney cancer

A study published in the journal Radiology from John Hopkins University in Baltimore, America provides evidence that cryoablation is as effective as surgery for treating early-stage kidney cancer as evidenced from 10-year survival rates. Percutaneous cryoablation is a minimally invasive procedure that destroys cancer cells by freezing the tumour using a probe inserted through the […]

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Cryoablation is safe and effective for small kidney tumours

A new study published in the American Journal of Roentgenology confirms that image-guided percutaneous cryoablation is a safe and efficacious treatment for selected small renal cell carcinoma (RCC) tumours. Cryoablation is a non-invasive technique, which involves ‘freezing’ the tumour using fine needles inserted through the skin (percutaneous). This technique has not yet been widely adopted […]

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Percutaneous ablation for small renal masses

Current guidelines recommend partial nephrectomy as the preferred treatment option for small renal masses. Percutaneous ablation, such as radiofrequency ablation and cryoablation, are mainly considered for patients who are not suitable for surgery or who have other conditions (co-morbidities) that make them unfit for surgery. There is currently a lack of evidence comparing partial nephrectomy […]

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Outcomes following partial nephrectomy and percutaneous ablation for small renal masses

A study published in European Urology presents retrospective data from the Mayo Clinic in America regarding their experience with partial nephrectomy, percutaneous radiofrequency ablation (RFA) and percutaneous cryoablation for small renal masses (less than 4 cm, stage cT1). Long-term follow-up data from 1798 patients with primary cT1N0M0 renal tumours were treated with partial nephrectomy, RFA […]

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Percutaneous ablation for localised kidney tumours

A recent study reported in European Urology by investigators at the Mayo Clinic in Rochester, Minnesota, USA compared partial nephrectomy with percutaneous ablation (radiofrequency ablation or cryoablation) in the treatment of 1422 patients with localised renal tumours, stage cT1. Patients were followed for at least 6 years. There were no significant differences in local recurrence, […]

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Percutaneous cryoablation for stage T1b tumours

A recent study published in Cardiovascular and Interventional Radiology this month looked at the use of percutaneous cryoablation for stage T1b (4.1-7.0 cm) renal cell carcinoma (RCC). This non-invasive technique, which involves ‘freezing’ the tumour using fine needles inserted through the skin (percutaneous), has not yet been widely adopted. The current study investigated the safety, […]

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Kidney cancer experts talk about the latest advances in treatments

The following interviews with kidney cancer experts discuss the latest advances in the treatment of renal cell carcinoma (RCC) and renal masses: No OS signal in axitinib + avelumab combination therapy – Dr Toni Choueiri, Dana Faber Cancer Institute, Boston, USA Treating renal masses with minimal invasive ablative technique – Dr Alessandro Volpe, Maggiore Della […]

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Cryoablation versus partial nephrectomy for early stage renal masses

A recent study, published in the Journal of Cancer, conducted a systematic review and meta-analysis of the outcomes data for the use of cryoablation versus partial nephrectomy for early stage (T1) renal tumours. The review showed that cryoablation is linked with poorer oncologic outcomes than partial nephrectomy, but patients who underwent cryoablation had lower rates […]

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