Clinical research cut by 87% at peak of COVID-19 pandemic

Research from University College London published in PLOS One estimated that at the peak of the COVID-19 pandemic, clinical research capacity may have been slashed by up to 87% in England. The researchers estimated that at a population infection rate of 10% (the peak in April for over a month) less than 400 of the […]

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National COVID-19 Research

The National Institute for Health Research (NIHR) have released a list of frequently asked questions about COVID-19 research taking place in the UK. So far, over 30,000 participants are taking part in a range of NIHR supported COVID-19 research studies across the UK. There are 21 new research studies into the novel coronavirus that have […]

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Kidney cancer clinical trials: What you need to know

In this article, Deb Maskens, founder of Kidney Cancer Canada and board director of the International Kidney Cancer Coalition (IKCC) recommends that patients with kidney cancer should be thinking about clinical trials at every step of their journey, not just after a line of therapy has stopped working for them. Ms Maskens, an advanced kidney […]

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Phase Ib cabozantinib plus atezolizumab combination study now open to kidney cancer patients in the UK

Based on promising efficacy findings, the COSMIC-021 clinical trial has been expanded from the original two indications (non-small cell lung cancer (NSCLC) and prostate cancer) and is now open to patients with renal cell carcinoma (RCC), urothelial cancer, breast cancer and ovarian cancer. The phase 1b, open-label trial assesses the combination of cabozantinib (Cabometyx) and […]

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Patient engagement in clinical development

The National Institute for Health Research (NIHR) is rolling out a new patient engagement service for the life sciences industry. This initiative, which has been in development for almost a year, aims to bring patients and life science companies together earlier in the clinical development process, before a study protocol is finalised. This will enable […]

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Barriers to cancer clinical trial enrolment

This review presents the findings of a meta-analysis of 13 cancer clinical trials representing nearly 9,000 patients to identify the barriers to clinical trial participation in the United States. Since this is a US study, some of the patient-related barriers regarding medical insurance do not apply for patients in the UK. Read the review in […]

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Advanced Kidney Cancer Centre of Excellence

The Advanced Kidney Cancer Center of Excellence from UroToday and GU OncToday delivers disease, treatment and guidelines information in this rapidly changing area. This series of articles explores ongoing clinical trials, including trials looking at biomarkers and genomic data, in addition to live conference coverage that will provide real-time perspectives from Dr Sumanta Kumar Pal and […]

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Results from a major study might lead to reduced animal testing by pharmaceutical companies

A major, groundbreaking study carried out by Elsevier, a global informatics company, in partnership with Bayer pharmaceuticals, investigating how well animal studies predict human safety may lead to reduced animal testing and better clinical results for patients. Researchers investigated the consistency between preclinical animal testing and observations made in human clinical trials. They looked at […]

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NHS to cut clinical trial bureaucracy to improve access to cutting-edge therapies

The NHS has introduced new processes to fast track research and improve access to cutting-edge therapies for patients by reducing the bureaucracy surrounding clinical trials. This bureaucracy has often been a barrier to getting hospitals to sign-up to multi-centre trials. The government has already created the Health Research Authority (HRA) as a single port of […]

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