Being overweight or obese is a well-known risk factor for kidney cancer. This study, published in the Journal of Urology, looked at how body mass index (BMI) affects the survival of a total of 50,717 kidney cancer patients. Overweight and obese patients were associated with improved survival compared to patients with normal BMI, while underweight […]
Researchers are constantly looking for biomarkers to help predict which patients will respond to each kidney cancer treatment. A study in Scandinavia has discovered a protein called tumour associated trypsin inhibitor (TATI) that is a biomarker for several tumours and for inflammation. High levels of TATI in the blood predicts an unfavourable outcome for many […]
This study looked at inflammatory biomarkers in the blood for the diagnosis of non-metastatic renal cell carcinoma (RCC). Inflammation is known to be associated with cancer, and there have been a number of studies that have looked at the relationship between cancer and inflammatory biomarkers. Inflammatory biomarkers such as the neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, lymphocyte/monocyte […]
A recent study published in the journal Cancer last month compared the survival of 8,988 kidney cancer patients from the American National Cancer Data Base to assess the impact of cancer spread to the lymph nodes in patients with stage III renal cell carcinoma (RCC). The researchers found that the 5-year survival rate of patients […]
A recent study published in the Journal of Endourology this month shows that obese and overweight patients do not experience higher complication rates or worse kidney function after key-hole (laparoscopic) surgery for stage 2 kidney cancer. This surgery can, therefore, be deemed feasible and safe in this group of patients. Nevertheless, obese and overweight patients […]
The results from a single-centre study reported in Clinical Genitourinary Cancer recently found that partial nephrectomy (nephron-sparing surgery) for localised renal cell carcinoma (RCC) may decrease the risk of cancer-specific mortality in some patients. The study was conducted in 1767 patients who underwent either partial or radical nephrectomy for RCC at the University of Brescia […]
A recent study published in Science Direct describes how a change in blood C-reactive protein (CRP) levels during the early phase of nivolumab treatment for metastatic renal cell carcinoma (mRCC) may be used to predict survival among patients with mRCC. Read more in Science Direct here
A recent study of 230 patients with sarcomatoid renal cell carcinoma (RCC) investigated pre-surgery neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, and platelet-lymphocyte ratio as biomarkers for the prediction of survival. Neutrophil-lymphocyte ratio was assessed 1 to 8 weeks after surgery, and percentage change from pre- to post-surgery was calculated. Pre-surgery neutrophil-lymphocyte ratio was a significant predictor of […]
A recent study, published in Scientific Reports last month, describes the validation of a new scoring system for renal cell carcinoma (RCC) called GRade, Age, Nodes and Tumour (GRANT). GRANT can be used to predict survival of RCC patients who have had a nephrectomy. In this study, GRANT was validated in over 73,000 kidney cancer […]
In a recent paper published in Cancer Medicine from researchers in Boston, USA, people with a large (10 cm or larger) renal cell carcinoma (RCC) tumour on their right kidney had a significant 15% decreased risk of death and better cancer-specific survival than left-sided RCC. Read more in Renal & Urology News here
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