Real world evidence as a complement to clinical trials

The review article highlights the usefulness of real world evidence to add substantially to the information available to the scientific and medical communities.

Randomised clinical trials have traditionally been the gold-standard for scientific evidence. However, randomised clinical trials are not able to answer all the questions necessary for clinical decision-making. Real world evidence refers to all the information and evidence collected outside traditional clinical trials, when the product or treatment is used in a routine clinical setting. Real world data can be found in disease or product registries (or databases), electronic health records, patient surveys, or personal health apps, and can add substantially to information used in clinical decision-making.

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