Personalising your cancer treatment using types of molecular tumour testing. Changes/mutations in genes encoding cellular signalling molecules, especially protein kinases, can result in the development of cancer. Drugs targeting mutant protein kinases can be effective for the treatment of some cancers. The sensitivity of such drugs is related to the genetic makeup of individual tumours. Information about the genetic makeup (a molecular profile) can be used to identify the targeted therapies that are designed to work better for a specific cancer tumour profile.