Novel therapies shaking up the treatment of kidney cancer

The following round table discussion between a panel of doctors (oncologists) discusses the recent advances in how renal cell carcinoma (RCC) is treated. Although treatment options for RCC have improved dramatically over the past decade, oncologists often face difficult decisions in selecting the right course of treatment for the individual patient, such as; which drug(s) […]

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EU approves nivolumab for renal cell carcinoma (RCC)

Nivolumab (Opdivo) has received approval for 2 new indications from the European Commission. Nivolumab is an programmed death receptor-1 (PD-1) immune checkpoint inhibitor that activates the immune system’s T cells to detect and attack cancer cells. The drug is already approved in Europe for use in previously treated patients with metastatic squamous non-small-cell lung cancer […]

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Cancer immunotherapy: Patient education is critical

In part I of this blog, Debra Madden, a 2-time cancer survivor (Hodgkin’s lymphoma and breast cancer) and Cancer Research Advocate, explains why it is important that patients understand that immunotherapy: Is not for every cancer patient Is not effective for every cancer patient Results in variable responses and variable time to response Requires different […]

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Lack of sleep helps tumours thrive

Researchers from Hospital Clínic De Barcelona in Spain, University of Chicago, and Memorial Sloan-Kettering Cancer Center in New York City, have presented the results from a recent study showing that lack of sleep can help tumours thrive at the European Association of Urology Congress in Munich, Germany. The study assessed the effects of sleep apnoea […]

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Cholesterol pill boosts cancer immunotherapy

Studies in mice suggest that tweaking cholesterol levels with avasimibe, a lipid-lowering drug, may boost the effectiveness of new immunotherapy drugs, such as nivolumab (Opdivo) and pembrolizumab (Keytruda). Adding avasimibe to PD-1 inhibitors improved tumour inhibition and increased survival in mice. Read more here.

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Non-aspirin NSAIDs associated with kidney cancer

A study presented at the 2016 Genitourinary Cancers Symposium last week warns that long-term use of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen but not aspirin or acetaminophen (Tylenol), appear to be associated with fatal cases of renal cell carcinoma (RCC). The data from the study suggest that non-aspirin NSAID use is associated with an […]

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Relapse of RCC can be possible years after initial treatment

A recent study published in Oncology Times by a group of researchers based in New Orleans, USA, has shown that renal cell carcinoma (RCC) may return years after successful treatment. In the study, 502 patients who were clear of cancer for at least 10 years were followed for late recurrences. Eight (8) patients had a […]

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Children’s kidney cancer diagnosed later in UK than Germany

In a recent study by Cancer Research UK and published in Archives of Disease in Childhood last week, Wilms’ tumours where diagnosed in the UK at a later and more advanced stage than those diagnosed in Germany. Wilms’ tumour is the most common form of childhood kidney cancer, affecting about 80 children a year in […]

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Adjuvant sunitinib or sorafenib for high risk kidney cancer

A study published in The Lancet last week reported that adjuvant treatment (treatment following surgery) with the VEGF receptor tyrosine kinase inhibitors sorafenib or sunitinib showed no survival benefit relative to placebo in a definitive phase 3 study. Furthermore, substantial treatment discontinuation occurred because of excessive toxicity, despite dose reductions. These results provide a strong […]

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Christy Watson talks about renal cancer

Christy talks about her experience and why she’s hosting her 3rd Green Ribbon Ball – she’s raised more than £75,000 for the charity. Get in touch at Renal Cancer Research Fund, Scotland. During the interview, Christy talks about her experience of being on a kidney cancer clinical trial, symptoms of kidney cancer, and the reason for starting […]

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