Developments in data for rare and less common cancers

Cancer52 and the National Cancer Registration and Analysis Service (NCRAS) at Public Health England (PHE) are delighted to be able to share a film and a report of the very successful Developments in Data for Rare and Less Common Cancers event held on 22nd May 2019. The report provides a written overview of the whole event and the film includes snippets […]

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Avelumab plus axitinib combination available via EAMS

It has just been announced that the avelumab plus axitinib combination has received positive scientific opinion for the Early Access to Medicines Scheme (EAMS) for the first-line treatment of advanced renal cell carcinoma (RCC). EAMS aims to give patients with life-threatening or seriously debilitating conditions access to medicines that do not yet have a marketing […]

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Alternative 2/1 sunitinib dosing schedule superior to 4/2 dosing schedule for metastatic kidney cancer

A recent study, published in Clinical Genitourinary Cancer reports a meta-analysis comparing the tolerability and efficacy of a 2 weeks on treatment/1 week off treatment sunitinib dosing schedule with the traditional 4/2 schedule in patients with metastatic renal cell carcinoma (mRCC). Data from 1173 patients were included in the meta-analysis. The study showed that progression-free […]

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Nivolumab and kidney cancer brain metastases

Results from a recent trial suggest that nivolumab has limited efficacy against previously untreated brain metastases in patients with metastatic renal cell carcinoma (mRCC). Around 10% of patients with metastatic RCC develop metastases in the brain. Since the results of this trial are negative and do not impact clinical practice, the study brings into question […]

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Mucinous tubular and spindle cell carcinoma

A recent study, published in Clinical Genitourinary Cancer, looked at the clinical features, treatment outcomes and genetic profiles of patients with mucinous tubular and spindle-cell carcinoma (MTSCC), a rare type of kidney cancer. There were 25 patients in the study, most of which had asymptomatic low-grade and localised tumours. Six patients had metastatic disease. The […]

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Liquid biopsy to detect cancer early

A new liquid biopsy test developed by scientists in the US, Denmark and the Netherlands and published in the journal Nature correctly detected the presence of cancer in the majority of cases, and identified the tissue with the primary tumour approximately 75% of the time. The test is a modified liquid biopsy test. A liquid […]

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Obesity now leading cause of four cancers

Cancer Research UK has released new findings showing that carrying excess weight causes more cases of kidney, bowel, ovarian and liver cancer than smoking. Almost a third of UK adults are obese and these people now outnumber those who smoke two to one. Being overweight or obese is now the leading cause of these four […]

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Research supports better integration of patient voice in health technology assessments

A report from Myeloma UK and the National Institute for Health and Care Excellence (NICE) outlines the findings from a study looking at how patient preferences could be more formally incorporated in health technology assessments (HTA). Feedback from a patient and family workshop demonstrated how myeloma impacts the lives of patients in different ways and […]

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Role of stereotactic ablative radiotherapy (SABR) for kidney cancer

This systematic review and meta-analysis of the literature for the use of stereotactic ablative radiotherapy (SABR) for renal cell carcinoma (RCC), looks at data from 372 patients (383 tumours), most of whom were inoperable. The study concluded that renal SABR is effective locally and is well tolerated for primary RCC, despite treatment of larger tumours […]

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Data-driven approach to personalised care

One of the greatest strengths of the NHS is its comprehensive datasets of the population from birth to death. A recent paper proposes a new model of cancer care and looks at how data could be examined and used at every stage of the treatment journey, from prevention and diagnosis through to treatment and recovery. […]

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