Patients with anxiety or depression prior to or at the time of surgery (197 patents, 10%) had significantly more complications 30 days after surgery. These patients also had slightly worse overall survival compared with patients without anxiety or depression. There were no differences between patients with anxiety and depression and those without in terms of recurrence, distant metastases, or death from RCC.
In conclusion, there are no significant association between cancer outcomes and anxiety and depression in patients who had surgery for localised clear cell RCC. However, further investigation is needed regarding anxiety or depression and overall survival.